Physiology and consequences of lung hyperinflation in COPD
نویسندگان
چکیده
منابع مشابه
Physiology and consequences of lung hyperinflation in COPD
Lung hyperinflation commonly accompanies expiratory flow limitation in patients with chronic obstructive pulmonary disease (COPD) and contributes importantly to morbidity and an impoverished quality of life. It is not surprising, therefore, that lung hyperinflation has become an important therapeutic target in symptomatic COPD patients. Acute dynamic increases in lung hyperinflation under condi...
متن کاملLung hyperinflation in COPD: applying physiology to clinical practice
In chronic obstructive pulmonary disease (COPD), worsening expiratory flow limitation together with alteration in the elastic properties of the lung are associated with progressive lung hyperinflation and gradual decline in the resting inspiratory capacity over time. Dynamic hyperinflation (DH) refers to the variable increase in end-expiratory lung volume (EELV) above the relaxation volume (VR)...
متن کاملLongitudinal changes in lung hyperinflation in COPD
PURPOSE COPD is characterized by an accelerated and progressive decline in forced expiratory volume in 1 second (FEV1) and lung hyperinflation. Although lung hyperinflation is the hallmark of COPD, data on the longitudinal changes in lung hyperinflation and any association with the decline in FEV1 are lacking. The aim of this study was to evaluate the longitudinal changes in lung hyperinflation...
متن کاملLung hyperinflation in COPD: the impact of pharmacotherapy
Improvement in airway function in response to bronchodilator therapy is generally confirmed by simple spirometry. However, improvements in maximal expiratory flow rates have been shown to correlate poorly with important patient-centred outcomes, such as reduced exertional dyspnoea and improved exercise performance. Recent studies have suggested that attendant reductions in end-expiratory lung v...
متن کاملCPAP decreases lung hyperinflation in patients with stable COPD.
BACKGROUND Dynamic hyperinflation, caused by expiratory flow limitation, markedly increases resting end-expiratory lung volume (functional residual capacity) in many COPD patients. OBJECTIVE To determine the impact and duration of impact of CPAP on hyperinflation and airway resistance in patients with stable COPD. METHODS In a case series, 21 patients underwent CPAP at 8 cm H(2)O for 15 min...
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ژورنال
عنوان ژورنال: European Respiratory Review
سال: 2006
ISSN: 0905-9180,1600-0617
DOI: 10.1183/09059180.00010002